The SphereJet™ system combines drop-on-demand, pressure assisted drop-on-demand, and continuous ink-jet drop generation methods that were developed in MicroFab’s research into ink-jet manufactured drug loaded microspheres. MicroFab has taken the three ink-jet based microsphere production methods and combined them into a single bench top research platform. The SphereJet™ system can be used to develop new materials and protocols based on the solvent extraction/evaporation method of microsphere manufacturing.
MicroFab’s development of olfaction measurement tools, a collaboration with NIST on precision vapor generation (link), and the basic research in a Phase I SBIR grant funded by NSF were used to develop our VaporJet™ precision vapor generation system. In this system, dilute solutions of explosives are deposited on a heater where they evaporate rapidly. The resulting vapors are carried to the outlet by gas stream controlled by a mass flow controller. Continuous or dose operation are available.
Phase I SBIR award on ultra-low volume crystallization
MicroFab receives a two year Phase I SBIR award from the National Institutes of Health for the development of an inkjet-based instrument to perform ultra-low volume crystallization screening of brain-derived GPCRs using the highly effective in meso lipid cubic phase (LCP) approach.
The collaborative work with NIST on the fabrication of test strips for testing the explosive trace detectors brought up the need to track the dispensed amount of material. The new Jetlab® 4xl-B system incorporates a micro-balance for accurate determination of the droplet mass, and tracks and records the results of the measurements.
Bio-printed Constructs for Battlefield Burn Repairs
MicroFab will develop, for a US Army funded project titled Bio-printed Constructs for Battlefield Burn Repairs, an in situ tissue engineering system for the repair of battlefield burn injuries. Inkjet-based dispensing systems, protocols, and materials that enable repair of life threatening battlefield burn injuries will be developed. This will allow army medical personnel to respond promptly in managing burn injuries using inkjet printed tissue engineered dermal repair constructs that are far superior to currently available autografts.